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Week 16 NFL DFS Cheat Sheet: Top Picks, Stacks, Values, Leverage Plays, Simulations, More

Justin Jefferson leads WRs in fantasy football points

Our crew has the Week 16 NFL DFS slate fully covered.

You’ll find all of the analysis for Sunday’s main slate below. Before you dive in, don’t forget to check out all the tools FantasyLabs offers.

Finally, make sure to check out all the projections available for purchase (Chris Raybon’s come included with a FantasyLabs subscription) within the FantasyLabs Models. Subscribers now have the option to purchase Derek Carty’s THE BLITZ from our Marketplace. Projections from One Week Season and Establish the Run are available if you’re a subscriber to those specific sites (our optimizer is a separate add-on feature).

You can also combine them to create your own aggregate projections:

NFL DFS Tools

  • Our SimLabs Lineup Generator allows you to create advanced DFS lineups in minutes using the power of simulation.
  • The Player Models house all of our projections plus loads of data.
  • The Lineup Builder has filters that can be added and adjusted to limit the player pool and better optimize your lineups. Filter options include player projections, custom performance trends, and more.
  • Our Lineup Optimizer generates lineups in seconds — anything from a pure optimization to a highly customized portfolio of lineups based on your own rules and settings.
  • Use the Vegas Dashboard to quickly find the spreads and totals for every game.
  • The DFS Trends tool allows you to access our massive database of stats to see how much value specific parameters have historically provided on DraftKings and FanDuel.
  • Utilize the Correlations Dashboard to see which positions and stats correlate the best.
Become an All-Access Member Today

Lineup builder and optimizer

Real-time DFS models & projections

Data-driven analysis & tutorials

 

Week 16 NFL DFS Content

Positional Breakdowns

Matt Martin dives deep into every position for this week’s slate.


Improve Your NFL DFS Game With the SimLabs Lineup Generator

Billy Ward provides tips and tricks to use our new NFL DFS simulations tool.


Main Slate Breakdown

Billy Ward looks over every relevant play and provides an in-depth analysis of everyone we should consider rostering.

This is who Billy and our projections are high on.


Top Model Picks and Value Plays

Zach Thompson analyzes who the FantasyLabs projections are highest on for Week 16.

See the top ceiling and value plays here.


Best OwnersBox Superflex Plays

Zach Thompson highlights his four favorite picks for OwnerBox’s Super Superflex format.

Read who he’s on here.


Top Stacks

Matt Martin breaks down some stacking options for Week 16.

Find out which combos pique his interest.


Top Leverage Picks

Alex Hunter discusses his favorite contrarian stack and one-off leverage plays.

Alex loves these contrarian plays for GPPs.


DFS Pick’em Simulation Tool

See who our DFS simulations tool likes for PrizePicks and Underdog Fantasy based on our play-by-play simulations.


Offensive Line vs. Defensive Line

Billy Ward breaks down which lines have the biggest edges this week.

See what lines have an advantage here.


One-Off GPP Plays

Looking for one-off GPP plays?

Try using our Minimalist Tournament Model.

Happy sweating!

 

Our crew has the Week 16 NFL DFS slate fully covered.

You’ll find all of the analysis for Sunday’s main slate below. Before you dive in, don’t forget to check out all the tools FantasyLabs offers.

Finally, make sure to check out all the projections available for purchase (Chris Raybon’s come included with a FantasyLabs subscription) within the FantasyLabs Models. Subscribers now have the option to purchase Derek Carty’s THE BLITZ from our Marketplace. Projections from One Week Season and Establish the Run are available if you’re a subscriber to those specific sites (our optimizer is a separate add-on feature).

You can also combine them to create your own aggregate projections:

NFL DFS Tools

  • Our SimLabs Lineup Generator allows you to create advanced DFS lineups in minutes using the power of simulation.
  • The Player Models house all of our projections plus loads of data.
  • The Lineup Builder has filters that can be added and adjusted to limit the player pool and better optimize your lineups. Filter options include player projections, custom performance trends, and more.
  • Our Lineup Optimizer generates lineups in seconds — anything from a pure optimization to a highly customized portfolio of lineups based on your own rules and settings.
  • Use the Vegas Dashboard to quickly find the spreads and totals for every game.
  • The DFS Trends tool allows you to access our massive database of stats to see how much value specific parameters have historically provided on DraftKings and FanDuel.
  • Utilize the Correlations Dashboard to see which positions and stats correlate the best.
Become an All-Access Member Today

Lineup builder and optimizer

Real-time DFS models & projections

Data-driven analysis & tutorials

 

Week 16 NFL DFS Content

Positional Breakdowns

Matt Martin dives deep into every position for this week’s slate.


Improve Your NFL DFS Game With the SimLabs Lineup Generator

Billy Ward provides tips and tricks to use our new NFL DFS simulations tool.


Main Slate Breakdown

Billy Ward looks over every relevant play and provides an in-depth analysis of everyone we should consider rostering.

This is who Billy and our projections are high on.


Top Model Picks and Value Plays

Zach Thompson analyzes who the FantasyLabs projections are highest on for Week 16.

See the top ceiling and value plays here.


Best OwnersBox Superflex Plays

Zach Thompson highlights his four favorite picks for OwnerBox’s Super Superflex format.

Read who he’s on here.


Top Stacks

Matt Martin breaks down some stacking options for Week 16.

Find out which combos pique his interest.


Top Leverage Picks

Alex Hunter discusses his favorite contrarian stack and one-off leverage plays.

Alex loves these contrarian plays for GPPs.


DFS Pick’em Simulation Tool

See who our DFS simulations tool likes for PrizePicks and Underdog Fantasy based on our play-by-play simulations.


Offensive Line vs. Defensive Line

Billy Ward breaks down which lines have the biggest edges this week.

See what lines have an advantage here.


One-Off GPP Plays

Looking for one-off GPP plays?

Try using our Minimalist Tournament Model.

Happy sweating!

 

About the Author

Justin Bailey is the Lead Editor for RotoGrinders and FantasyLabs. He’s been playing DFS since 2013 and specializes in small-field NFL and PGA contests. Justin qualified for the DraftKings Fantasy Golf World Championship in 2023.